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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
34.24
Human Site:
T175
Identified Species:
50.22
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
T175
A
Y
T
H
Q
V
V
T
R
W
Y
R
A
P
E
Chimpanzee
Pan troglodytes
XP_518193
305
34323
A157
G
V
G
V
D
M
W
A
V
G
C
I
L
A
E
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
T175
A
Y
T
H
Q
V
V
T
R
W
Y
R
A
P
E
Dog
Lupus familis
XP_850424
354
39795
T183
A
Y
T
H
Q
V
V
T
R
W
Y
R
A
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
T175
A
Y
T
H
Q
V
V
T
R
W
Y
R
A
P
E
Rat
Rattus norvegicus
P51952
329
37122
T167
A
Y
T
H
Q
V
V
T
R
W
Y
R
A
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
E160
T
R
W
Y
R
A
P
E
L
L
F
G
A
R
M
Chicken
Gallus gallus
P13863
303
34670
V157
A
R
A
F
G
I
P
V
R
V
Y
T
H
E
V
Frog
Xenopus laevis
P20911
352
39672
T181
I
Y
T
H
Q
V
V
T
R
W
Y
R
S
P
E
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
T166
L
Y
S
H
Q
V
A
T
R
W
Y
R
A
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
T175
I
Y
T
H
H
V
V
T
R
W
Y
R
S
P
E
Honey Bee
Apis mellifera
XP_395800
321
36188
E161
T
R
W
Y
R
A
P
E
L
L
Y
G
A
R
L
Nematode Worm
Caenorhab. elegans
P34556
332
38277
T184
V
Y
T
H
E
V
V
T
L
W
Y
R
A
P
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
A150
K
L
A
D
F
G
L
A
R
A
F
G
I
P
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
A172
K
F
T
H
Q
V
F
A
R
W
Y
R
A
P
E
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
I160
A
I
P
A
P
H
E
I
L
T
S
N
V
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
20
86.6
80
N.A.
80
13.3
80
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
26.6
26.6
93.3
86.6
N.A.
86.6
26.6
86.6
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
13.3
N.A.
73.3
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
80
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
44
0
13
7
0
13
7
19
0
7
0
0
63
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
7
13
0
0
0
0
0
7
69
% E
% Phe:
0
7
0
7
7
0
7
0
0
0
13
0
0
0
0
% F
% Gly:
7
0
7
0
7
7
0
0
0
7
0
19
0
0
0
% G
% His:
0
0
0
63
7
7
0
0
0
0
0
0
7
0
0
% H
% Ile:
13
7
0
0
0
7
0
7
0
0
0
7
7
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
7
0
0
0
0
7
0
25
13
0
0
7
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
7
0
7
0
19
0
0
0
0
0
0
69
0
% P
% Gln:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
0
13
0
0
0
69
0
0
63
0
13
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
7
0
13
0
0
% S
% Thr:
13
0
57
0
0
0
0
57
0
7
0
7
0
0
7
% T
% Val:
7
7
0
7
0
63
50
7
7
7
0
0
7
7
13
% V
% Trp:
0
0
13
0
0
0
7
0
0
63
0
0
0
0
0
% W
% Tyr:
0
57
0
13
0
0
0
0
0
0
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _